Custom Organic Synthesis
Synthesis Services
- Custom small molecule synthesis — milligram to multigram scale
- Complex and multi-step synthetic routes
- Medicinal chemistry and lead optimization support
- Analog and derivative library synthesis
- Chiral synthesis and asymmetric methodologies
- Proprietary chiral resolution technology — separation of racemic mixtures into optically pure enantiomers
- Building block synthesis and functionalization
- Natural product analog synthesis
- Heterocyclic chemistry
- Protecting group chemistry and orthogonal deprotection strategies
Analytical & Characterization Services
- Nuclear Magnetic Resonance (NMR) spectroscopy — structural confirmation
- Liquid Chromatography-Mass Spectrometry (LC-MS)
- Analytical HPLC — purity assessment
- Preparative HPLC — compound purification
- ISCO automated flash chromatography purification
- Full Certificate of Analysis (CoA) provided with every compound
For SBIR/STTR & Federally Funded Biotechs
If your company holds NIH, NSF, NCI, DARPA, or DOD funding, your grant terms likely require domestic suppliers for contracted chemistry services. J&W Pharmlab is 100% US-based — every synthesis step, every analytical run, and every team member operates from our Pennsylvania facility.
We understand the realities of small biotech: tight milestone deadlines, lean teams, and grant budgets that don't allow for wasted iterations. Our role is to function as your external chemistry department — responsive, expert, and fully compliant
Why SBIR/STTR Companies Choose J&W Pharmlab
- US-based synthesis fully compliant with NIH, NSF, DOD, and NCI grant requirements
- All work performed on US soil — eligible documentation provided for grant reporting
- NDA executed rapidly — your proprietary structures are protected from day one
- Itemized, grant-compatible invoices provided for every project
- Named PhD chemist assigned to your project — available by phone and email during US business hours
- Flexible project scope — single compounds, focused libraries, or ongoing medicinal chemistry retainers
- 24-hour response commitment on all inquiries and quote requests
For AI-Driven Drug Discovery Companies
AI drug discovery platforms can generate hundreds of novel molecular candidates in a single optimization cycle. The bottleneck is no longer ideation — it is synthesis. J&W Pharmlab is built to be the chemistry execution layer your AI platform needs.
We work with computational and AI-driven teams who need a CRO that speaks their language: SMILES strings, rapid iteration, SAR data turnaround, and electronic data delivery compatible with machine learning pipelines.
How We Support AI Drug Discovery Workflows
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Your Need |
What J&W Pharmlab Delivers |
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Fast iteration cycles |
Quote within 24 hours of structure submission. Compounds delivered on aggressive timelines without sacrificing quality. |
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Analog series synthesis |
Submit a series of SMILES, receive a prioritized synthesis plan and phased delivery schedule. |
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Chemist collaboration |
Our PhD chemists engage in scientific discussion — flagging synthetic challenges, proposing feasible alternatives, and optimizing routes. |
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Electronic data delivery |
NMR, LC-MS, and HPLC data delivered in structured digital formats ready for your ML pipeline. |
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IP protection |
All synthesis performed in the US. No foreign lab exposure. Your candidate structures stay confidential. |
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Flexible volume |
From single exploratory compounds to focused libraries — we scale with your discovery cadence. |
Project Types We Support
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Drug Discovery & Development
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Research & Specialty Chemistry
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